Sleep and Activity Patterns as Transdiagnostic Behavioral Biomarkers in Psychiatry: Longitudinal Observational Study From the DeeP-DD Study.

ABSTRACT:

Background

Despite widespread use of symptom rating scales in psychiatry, these tools are limited by reliance on self-report, infrequent administration, and lack of predictive power. This constrains clinicians' ability to monitor illness trajectories or anticipate adverse outcomes like relapse. Actigraphy, a passive wearable-based method for measuring sleep and physical activity, offers objective, high-resolution behavioral data that may better reflect symptom fluctuations. Prior research has shown associations between actigraphy features and mood or psychosis symptoms, but most studies have focused on narrow diagnostic groups or fixed time windows, limiting clinical translation.

Objective

This study aims to examine whether actigraphy-derived sleep and activity features corr

SUBMITTER: Hamitouche D 

PROVIDER: S-EPMC12617961 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature