Economics of hypothalamic obesity in patients with craniopharyngioma and other rare sellar/suprasellar tumors.

ABSTRACT:

Background

Rapid and abnormal weight gain resulting in severe persistent obesity due to physical, tumor- and/or treatment-related damage to the hypothalamus, is called acquired hypothalamic obesity (aHO), and is often linked to craniopharyngioma and/or sellar/suprasellar tumors. Here, we examine the healthcare resource use (HCRU) and costs of aHO following treatment of these tumors.

Methods

We used a retrospective matched cohort design with German statutory health insurance data on 5.42 million people from 2010 to 2021. We applied a novel three-step approach using diagnostic and prescription data to identify patients with treatment- or tumor-related (TTR)-aHO. We measured HCRU and costs across hospitalizations, outpatient visits, visits per specialist group, and outpatient p

SUBMITTER: Witte J 

PROVIDER: S-EPMC12618323 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature