Impact of pre-transplant veno-venous extracorporeal membrane oxygenation on post-lung transplant infections.

ABSTRACT: Bridging critically ill patients to lung transplantation with veno-venous extracorporeal membrane oxygenation (VV-ECMO) may increase infection risk, yet its impact on post-transplant outcomes remains unclear. We evaluated the incidence, timing, and risk factors for respiratory and bloodstream infections in patients supported with pre-operative VV-ECMO and assessed one-year survival. We conducted a retrospective cohort study of 293 adult lung transplant recipients at a single center between January 2018 and June 2023. Thirty-seven patients received pre-transplant VV-ECMO, and 256 did not. We compared the incidence and median time to first respiratory and bloodstream infections and estimated one-year survival. Cox proportional hazard models identified independent predictors of infection. VV-

SUBMITTER: Kaniuk JK 

PROVIDER: S-EPMC12618338 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature