Prediction accuracy of femoral and tibial stress and strain using statistical shape and density model-based finite element models in paediatrics.

ABSTRACT: Computed tomography (CT)-based finite element (FE) models can non-invasively assess bone mechanical properties, but their clinical application in paediatrics is limited due to fewer datasets and models. Statistical Shape-Density Model (SSDM)-based FE models using statistically inferred shape and density have application to predict bone stress and strains; however, their accuracy in children remains unexplored. This study assessed the accuracy of stress-strain distributions estimated from SSDM-based FE models of paediatric femora and tibiae. CT-based FE models used geometry and densities derived from 330 CT scans from children aged 4-18 years. Paediatric SSDMs of the femur and tibia were used to predict bone geometries and densities from participants' demographics and linear bone measuremen

SUBMITTER: Xu Y 

PROVIDER: S-EPMC12618425 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature