Risk for neurocognitive impairment in Korean childhood cancer survivors.

ABSTRACT: Background Neurocognitive impairment is one of the serious treatment-related late complications of childhood cancer survivors (CCS). This study aimed to evaluate neurocognitive impairment of Korean CCS at their adolescent and young age for whom little was known. Method We recruited 720 Korean CCS diagnosed with primary cancer before the age of 19 years and 222 siblings of CCS. We measured neurocognitive function using the Korean version of Neurocognitive Questionnaire (K-NCQ) composed of four subdomains, with cut-off level of impairment set at the upper 10% of score distribution among sibling group. We evaluated the risk of neurocognitive impairment in CCS as compared with sibling by multiple logistic regression analysis. Results Average (standard deviation) ages of CCS at cancer diagnosis

SUBMITTER: Lee YS 

PROVIDER: S-EPMC12618568 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature