Troponin at presentation: A key predictor of chronic myocardial impairment post-myocarditis-A prospective cohort study.

ABSTRACT:

Objectives

Myocarditis may lead to persistent myocardial impairment. We evaluated whether admission troponin I and inflammatory biomarkers predict one-year myocardial impairment using global longitudinal strain (GLS) as the reference outcome.

Design

Prospective, single-center cohort study (2013-2023); approved by the Kaplan Medical Center Institutional Review Board (KMC-10-0068).

Setting

Kaplan Medical Center, Israel.

Participants

A total of 115 patients were admitted with myocarditis, defined by ESC criteria.

Main outcome measures

Admission biomarkers included troponin I (pg/mL), white blood cells (WBC; × 10⁹/L), C-reactive protein (CRP; mg/L), and erythrocyte sedimentation rate (ESR; mm/h). One-year myocardial function was assessed by speckl

SUBMITTER: Ayyad O 

PROVIDER: S-EPMC12618808 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature