Effectiveness of antiemetic regimens in controlling chemotherapy induced nausea and vomiting during hematopoietic stem cell transplantation.

ABSTRACT: This study aimed to evaluate the efficacy of antiemetic regimens in controlling chemotherapy-induced nausea and vomiting (CINV) among patients with haematological malignancies undergoing highly (HEC) or moderately emetogenic chemotherapy (MEC) as part of conditioning for hematopoietic stem cell transplantation (HSCT). A prospective cohort study was conducted from November 2022 to July 2024 at University Hospital Virgen del Rocío, Seville (Spain). Adult patients receiving HEC or MEC conditioning regimens were assessed for CINV control using a symptom questionnaire adapted from the validated questionnaire Pro-CTCAE. Effectiveness was measured by complete response (CR) and complete protection (CP) from nausea/emesis across acute (chemotherapy days) and delayed (five days post-chemotherapy) ph

SUBMITTER: Suarez-Casillas P 

PROVIDER: S-EPMC12618924 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature