Pancreatic Ductal Adenocarcinoma After Hepatitis C Infection.

ABSTRACT:

Importance

Although hepatitis C virus (HCV) is an oncovirus, its association with the risk of pancreatic ductal adenocarcinoma (PDAC) is unclear. In addition, it is unknown whether there is differential risk for PDAC across HCV genotypes.

Objective

To assess the association between chronic HCV and PDAC.

Design, setting, and participants

This retrospective, national, population-based cohort study was conducted across Veterans Health Administration (VA) sites. The study included veterans with HCV testing documented in the VA or VA-linked Medicare with at least 1 inpatient or outpatient visit between October 1, 2001, and September 30, 2020. Patients were followed-up for at least 18 months after this visit. Data were analyzed from October 2023 to September 2025.

Exposu

SUBMITTER: Levinson RN 

PROVIDER: S-EPMC12619103 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature