Association between baseline BMI and in-hospital mortality in critically ill cardiac surgery patients: a retrospective cohort study.

ABSTRACT:

Background

BMI-mortality associations in critically ill cardiac surgery lack precise threshold characterization. We investigated the baseline BMI and in hospital mortality in ICU cardiac surgery patients.

Methods

We included 8032 cardiac surgery patients from eICU (208 US hospitals, 2014-2015). Focus exposure: BMI; key outcome: 30-day mortality. Adjustments encompassed demographics, laboratory values, APACHE-IV scores, comorbidities, and interventions. Nonlinear patterns were examined via penalized spline-fitted generalized additive modeling.

Results

Among 8,032 patients (BMI: 29.6 ± 6.8 kg/m²), in-hospital mortality occurred in 289 cases (3.6%). Standard linear modeling detected no BMI-mortality relationship (OR = 0.99, 95% CI 0.97-1.01, P = 0.210). Conver

SUBMITTER: Peng GG 

PROVIDER: S-EPMC12619241 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature