Effects of Jinhua instant dark tea in patients with type 2 diabetes mellitus: study protocol for a multicenter, open-label, randomized controlled trial.

ABSTRACT:

Backgrounds

The global prevalence of diabetes is rising, with many patients experiencing challenges in medication adherence and adverse effects associated with synthetic drugs. Natural products have attracted interest as potential preventive or adjunctive therapies. Jinhua dark tea (JHTea), a naturally fermented Chinese tea, has shown promising glucose-lowering and lipid-modulating effects in vitro and animal studies, but robust clinical evidence is lacking. This study is the first large-scale, long-term randomized controlled trial (RCT) evaluating JHTea as an adjunctive therapy for type 2 diabetes mellitus (T2DM).

Methods

This multicenter, open-label parallel randomized controlled trial across three centers in China will enroll 264 participants aged 40-70 years with T2DM, e

SUBMITTER: Chen N 

PROVIDER: S-EPMC12619345 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature