Prospective associations between the trajectory of the Chinese visceral adiposity index and risk of new-onset heart failure.

ABSTRACT:

Background

The Chinese Visceral Adiposity Index (CVAI), a straightforward surrogate measure of visceral fat, is significantly associated with the risk of cardiovascular disease (CVD) in the general population. This study aimed to evaluate the association of the trajectory of the Chinese visceral adiposity index with new-onset heart failure (HF) risk.

Methods

This prospective cohort study included 76,822 participants who were free of HF or cancer up to 2012. The CVAI was calculated using the age, body mass index, waist circumference, and metabolic parameters of the participants, and latent mixed modelling was used to identify the trajectory of CVAI during the exposure period (2006-2012). Cox proportional hazard models were used to calculate the hazard ratio (HR) and 95% confi

SUBMITTER: Wu K 

PROVIDER: S-EPMC12619362 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature