Effects of dietary management for medium-chain acyl-CoA dehydrogenase deficiency (MCADD) on eating behaviour in childhood, adolescence and young adulthood.

ABSTRACT:

Background

Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is an autosomal recessive disorder of ß-oxidation. A loss of enzyme function results in impaired breakdown of medium-chain fatty acids. The main treatment involves a dietetic approach to ensure adequate food intake and avoiding fasting. Diseases treated with a strict diet during childhood are often associated with eating problems. However, research in this area is very limited. This exploratory observational study aimed to examine the effects of dietary management and the underlying recommendations for MCADD on eating behaviour, as well as their subsequent impact on family life.

Methods

Paediatric and young adult patients (age 8-25) with MCADD and their caregivers at the University Hospital Muenster were inclu

SUBMITTER: Banaszak P 

PROVIDER: S-EPMC12619415 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature