The association between plasma omega-3 fatty acids and suicidal ideation/self-harm in the United Kingdom Biobank.

ABSTRACT:

Background

Self-harm is a significant public health concern, with increasing prevalence globally. Omega-3 fatty acids (FAs), particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are known for their health benefits, including potential mental health improvements. This study explores the association between omega-3 FAs and self-harm behaviors using data from the UK Biobank (UKBB).

Objectives

To investigate the relationship between plasma levels of omega-3 FAs and various measures of self-harm, including passive suicidal ideation and deliberate self-harm, within a large cohort study.

Methods

This observational study analyzed data from a random subset of 258,012 participants with plasma omega-3 FA levels, covariate data, and self-harm records. Omega-3

SUBMITTER: Franco WG 

PROVIDER: S-EPMC12619467 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature