Antimicrobial resistance profiles and molecular characterization of extended-spectrum β-lactamase/AmpC-harboring Klebsiella pneumoniae isolated from clinically ill dogs and cats in South Korea.

ABSTRACT:

Background

The emergence of ESBL/AmpC-producing K. pneumoniae is a significant concern in humans and veterinary medicine. This study aims to ascertain the antimicrobial resistance profiles and molecular characteristics of ESBL/AmpC-producing K. pneumoniae isolated from diseased companion animals during 2018-2023 in South Korea.

Methods

The obtained isolates (dogs, n = 130 and cats, n = 30) from urine, genital organs, diarrheal feces, skin/ear, and respiratory tract were assessed for antimicrobial susceptibility by broth microdilution. Molecular characteristics were determined by polymerase chain reaction (PCR), multi-locus sequence typing (MLST), and pulsed-field gel electrophoresis (PFGE).

Results

Among the tested antimicrobials, the highest resistance rates were dem

SUBMITTER: Hwang YJ 

PROVIDER: S-EPMC12619490 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature