Sustained effect of a multifaceted VAP prevention program over more than seven years including the COVID-19 pandemic.

ABSTRACT: We report the long-term impact of a multifaceted intervention bundle containing nine measures to reduce the incidence of ventilator-associated pneumonia (VAP) in mechanically ventilated patients admitted to the intensive care division at Geneva University Hospitals over a prolonged follow-up period of more than seven years, including the COVID-19 pandemic. The original study included a follow-up of 11 months and showed a marked decrease in VAP incidence. We compared the five pre-defined time periods (pre-intervention, intervention, post-intervention, prolonged follow-up, and COVID-19 pandemic period) using a Poisson model. The incidence of VAP per 1000 ventilator days reduced from 24.3 (95% confidence interval [CI] 18.8-30.9) in the pre-intervention period to 3.9 (95%CI 2.0-6.8) in the pos

SUBMITTER: Buchler AC 

PROVIDER: S-EPMC12619505 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature