Identifying sex-linked metabolomic biomarkers in fish gonads after bacterial infection.

ABSTRACT:

Purpose

Fish aquaculture faces sustainable production challenges. Among them are the pathogenic outbreaks that can compromise the health of the stocks from various perspectives, including broodstock reproduction. This study focused on identifying the metabolite alterations produced after a bacterial infection by Vibrio anguillarum in the gonads of European seabass (Dicentrarchus labrax). Sex-related response to the infection challenge was studied using a metabolomics approach.

Method

The metabolome of testes and ovaries of adult fish were extracted and analyzed after 48 h of bacterial exposure by ultra-high-performance liquid chromatography-mass spectrometer using negative-mode electrospray ionization (ESI) (UHPLC-MS, Vanquish Horizon UHPLC coupled to a Thermo Fisher Scienti

SUBMITTER: Caballero-Huertas M 

PROVIDER: S-EPMC12619773 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature