Prognostic Impact of Different Definitions of White-Coat Hypertension.

ABSTRACT:

Background

Different definitions of white-coat hypertension (WCH) may explain its variable outcome across studies.

Methods

In an Italian study started in 1986, we followed 3,153 people with (office blood pressure (BP) >=140/90 mmHg) and 457 without office hypertension for a mean of 10.4 years. None had previous cardiovascular disease. All underwent 24-h ambulatory BP (ABP) monitoring. We defined white-coat hypertension (WCH) as an average 24-h ABP < 130/80 mmHg or <125/75 mmHg. The primary outcome was a composite of major adverse cardiovascular events (MACE) and all-cause mortality.

Results

Baseline office BP was 156/97 mmHg in people with and 127/81 mmHg without hypertension. At follow-up, MACE events were 344 and 23, and all-cause deaths were 318 and 24 in people wi

SUBMITTER: Verdecchia P 

PROVIDER: S-EPMC12620022 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature