Increased Circulating Interleukin Concentrations in Type 2 Diabetes: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objectives

This work aimed to quantitatively evaluate circulating interleukin concentration data available for patients with Type 2 diabetes.

Methods

We performed a systematic review using PubMed, Web of Science, and the Cochrane Library. Original studies reporting data on circulating interleukin concentrations in at least one group of patients with Type 2 diabetes (obese Type 2 diabetes [OBD], overweight Type 2 diabetes [OWD], or lean Type 2 diabetes [LD]) and healthy weight controls (HWCs) were included. Data were extracted from 43 included studies uniquely encompassing 2646 patients with Type 2 diabetes and 6605 HWCs by independent investigators. We used a random-effects model to pool data in the Comprehensive Meta-Analysis Version 2 software. Effect sizes (ESs) were calc

SUBMITTER: Cao C 

PROVIDER: S-EPMC12620103 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature