Structural and Functional Brain Changes in Children and Adolescents With Obesity.

ABSTRACT: Obesity, particularly pediatric obesity, has dramatically increased over the last three decades, with a wide range of detrimental health outcomes, including negative consequences for brain neurodevelopment. The present article reviewed magnetic resonance imaging studies between January 2011 and March 2024 examining the brain's role in pediatric obesity, including parental influences and diverse interventions. A literature search identified 97 eligible MRI studies in the pediatric population. Findings suggest that altered brain structures and functions in pediatric obesity are strongly dependent on the developmental stage of children and adolescents. The function and structure of limbic regions, such as the hippocampus, amygdala, and striatum, as well as the prefrontal cortex, seem to be pa

SUBMITTER: Zhao S 

PROVIDER: S-EPMC12620109 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature