Flow-suppressed 2D spin-echo imaging with high tolerance to B₁ inhomogeneity using hyperbolic secant pulses.

ABSTRACT:

Purpose

To demonstrate flow-suppressed two-dimensional (2D) spin-echo and spin-echo diffusion echo-planar imaging (EPI) sequences using hyperbolic secant (HS) pulses for both π/2 excitation and π refocusing.

Theory and methods

A theoretical framework to derive phase dispersion of moving spins under π/2 excitation and π refocusing using HS pulses was described. Numerical simulations were performed to verify the validity of the theoretical analysis. All experiments were performed on a 3T clinical scanner. Phantom and human-brain imaging was performed using 2D spin-echo sequence, and liver imaging was performed using 2D spin-echo diffusion EPI. The signal-to-noise ratio and residual blood flow signal of the proposed sequences were compared with those of conventional spin-echo s

SUBMITTER: Keum JY 

PROVIDER: S-EPMC12620147 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature