Development of an immunochromatographic test for serodiagnosis of human sparganosis.

ABSTRACT: Sparganosis is a parasitic zoonosis caused by the larval plerocercoid (sparganum) of tapeworms in the genus Spirometra. Humans become infected by ingesting raw or undercooked meat from second intermediate or paratenic hosts such as frogs, snakes, and wild boars by drinking water contaminated with cyclopoid copepods carrying the larval procercoid, or by applying frog meat poultices. The gold standard for diagnosis remains the molecular confirmation of plerocercoids in surgically removed specimens. However, because these larvae migrate in subcutaneous tissues and the central nervous system elicit a strong IgG antibody response, serological tests can provide valuable diagnostic support. Although several IgG antibody detection assays have been developed, they are often time consuming and requi

SUBMITTER: Harasan J 

PROVIDER: S-EPMC12620320 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature