Design of a dual-responsive system based on ferrocene and porous Fe₂O₃ microspheres for therapeutic applications.

ABSTRACT: This paper reports the development of an advanced dual-stimuli-responsive drug-delivery system designed to enhance the precision and efficiency of targeted therapies. The system integrates the unique properties of ferrocene and porous iron oxide microspheres (P-Fe₂O₃) to respond to reactive oxygen species and external magnetic fields. Ferrocene, with its well-known redox properties, facilitates selective drug release in oxidative environments commonly found in tumor tissues, while P-Fe₂O₃ imparts magnetism and porosity for improved targeting and controlled release under magnetic stimuli. P-Fe₂O₃ is synthesized using an environmentally friendly, continuous, and scalable spray pyrolysis technique, whereas ferrocene-based polym

SUBMITTER: Seo D 

PROVIDER: S-EPMC12620346 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature