Reactive oxygen species are involved in inhibition of photoreactivation of Staphylococcus aureus irradiated with 222-nm Far ultraviolet C.

ABSTRACT: Ultraviolet-C (UV-C) at a wavelength of 254 nm is used for disinfection but cannot be used in dwelling space because it is harmful to the human body, while 222-nm Far UV-C shows germicidal effect and poses little hazardous effect to human. Formation of cyclobutane pyrimidine dimers (CPD) of DNA is a main mechanism of UV-C germicidal effect. CPD formed by irradiation with 254-nm UV-C is repaired and bacterial proliferation is recovered by photoreactivation. In this study, we investigated photoreactivation of Staphylococcus aureus irradiated with 222-nm Far UV-C. The proliferative effect of 222-nm Far UV-C irradiated S. aureus by photoreactivation was inferior to that of irradiated with 254-nm UV-C. The 254-nm UV-C wavelength and 222-nm Far UV-C induced CPD in S. aureus cells, and the same l

SUBMITTER: Fukushi R 

PROVIDER: S-EPMC12621088 | biostudies-literature | 2025 Nov-Dec

REPOSITORIES: biostudies-literature