Antiviral susceptibility monitoring: testing algorithm, methods, and findings for influenza season, 2023-2024.

ABSTRACT: Antiviral susceptibility monitoring is integral to influenza surveillance conducted by CDC in collaboration with partners. Here, we outlined the algorithm and methods used for assessing antiviral susceptibility of viruses collected during 2023-2024 season. Virus specimens were provided by public health laboratories in the United States (US) and by laboratories in other countries that belong to the Pan American Health Organization. In the US, antiviral susceptibility surveillance conducted nationally is strengthened by sequence-only analysis of additional viruses collected at a state level. Viral genome sequence analysis was the primary approach to assess susceptibility to M2 blockers (n = 5123), neuraminidase (NA) inhibitors (n = 6874), and a polymerase acidic protein (PA) inhibitor (balox

SUBMITTER: Patel MC 

PROVIDER: S-EPMC12621569 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature