One Health at the Last Mile: Multi-scale Predictors of <i>Schistosoma japonicum</i> Infection in Southwest China across Two Decades of Control.

ABSTRACT: In China, schistosomiasis is targeted for elimination. As the country approaches elimination, it is critical to evaluate how the dynamics of transmission are changing in remaining pockets of disease. We have been studying areas of schistosomiasis reemergence and persistence in Sichuan, China since 2007. This study used gradient boosting machines to identify key predictors of infection across two periods, 2007-2010, a period when schistosomiasis had reemerged, and 2016-2019, a period when schistosomiasis was approaching elimination. We also evaluated how key risk factors have shifted over time and whether combinations or predictors amplified risk. We considered predictors describing agriculture, domestic animals, socio-economic status, water and sanitation infrastructure and demographics at

SUBMITTER: Zou WW 

PROVIDER: S-EPMC12622095 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature