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Association between visceral adiposity index and cognitive dysfunction in US participants derived from NHANES data: A cross-sectional analysis.


ABSTRACT: This study examines the cross-sectional association between the Visceral Adiposity Index (VAI) and domain-specific cognitive performance in US older adults. We analyzed data from 1323 participants aged ≥ 60 years in the National Health and Nutrition Examination Survey (NHANES) 2011 to 2014. Cognitive function was assessed with CERAD Word‑List Learning (memory/learning), Animal Fluency Test (semantic fluency/executive function), and the Digit Symbol Substitution Test (DSST; processing speed/attention). We fitted a sequence of multiple linear regression models: model 1 (crude), model 2 (adjusted for demographic covariates), model 3 (further adjusted for lifestyle factors), and model 4 (additionally adjusted for clinical comorbidities). Effect estimates are presented as β coefficients with 95

SUBMITTER: He L 

PROVIDER: S-EPMC12622683 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature