Development of a prediction model for urinary tract infection risk after open reimplantation in children with primary unilateral vesicoureteral reflux: A multicentre study.

ABSTRACT:

Objectives

To develop a predictive model for symptomatic postoperative febrile urinary tract infections (UTIs) in children undergoing open reimplantation for vesicoureteral reflux (VUR) and evaluate the association with VUR recurrence.

Patients and methods

This multicentre retrospective study included children with unilateral VUR (grades III-V) who underwent open Cohen or Lich-Gregoir reimplantation (2010-2022), had recurrent febrile UTIs, and ≥1 year follow-up. Analyses used 10-pooled multiple imputation, with complete case for sensitivity. Full and Least Absolute Shrinkage and Selection Operator (LASSO) Weibull regression models with centre clustering, bootstrapping, and 10-fold cross-validation identified predictors. Prediction used demographic, clinical, procedural and a

SUBMITTER: Ismail K 

PROVIDER: S-EPMC12623004 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature