Identification of robust species-specific marker genes for the demarcation of the <i>Klebsiella pneumoniae-quasipneumoniae-variicola</i> complex.

ABSTRACT: Introduction. Klebsiella pneumoniae, Klebsiella quasipneumoniae and Klebsiella variicola are closely related species (collectively referred to as 'PQV') but exhibit distinct clinical presentations and epidemiological profiles. These distinctions are important for proper diagnosis and treatment of infections and other Klebsiella-related diseases. The ability to differentiate between these species is becoming more important as we better understand their unique roles in disease.Hypothesis/Gap statement. Despite the importance of accurate taxonomic classifications, both traditional and modern laboratory techniques fail to accurately delineate between the PQV species, which can lead to treatment failures. Conversely, taxonomy via whole-genome sequencing

SUBMITTER: Galib M 

PROVIDER: S-EPMC12623006 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature