Dynamic MR of Muscle Contraction During Electrical Muscle Stimulation: Potential Application to the Evaluation of Neuromuscular Diseases.

ABSTRACT: Thanks to the rapid evolution of therapeutic strategies for muscular and neuromuscular diseases, the identification of quantitative biomarkers for disease identification and monitoring has become crucial. Magnetic resonance imaging (MRI) has been playing an important role by noninvasively assessing structural and functional muscular changes. This exploratory study investigated the potential of dynamic MRI during neuromuscular electrical stimulation (NMES) to detect differences between healthy controls (HCs) and patients with metabolic and myotonic myopathies. The study included 14 HCs and 10 patients with confirmed muscular diseases. All individuals were scanned with 3 T MRI with a protocol that included a multi-echo gradient echo sequence for fat fraction quantification, multi-echo spin-e

SUBMITTER: Santini F 

PROVIDER: S-EPMC12623070 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature