Developing educational materials to aid in Alzheimer's blood biomarker disclosure.

ABSTRACT:

Introduction

A crucial step before clinical use of Alzheimer's disease (AD) blood biomarkers is the development of effective methods for disclosing results. This mixed-method study developed educational materials to disclose the dementia risk based on plasma phosphorylated tau (p-tau) results.

Methods

Participants diagnosed with mild cognitive impairment (MCI; n = 8) and their care partners (n = 7) participated in focus groups discussing the utility of an educational tool and communication preferences. Focus groups were recorded, transcribed, and analyzed using NVivo, with two independent coders conducting thematic analysis.

Results

Participants rated the materials highly regarding value and comprehension. Thematic analysis revealed confusion about demen

SUBMITTER: Romano RR 

PROVIDER: S-EPMC12623145 | biostudies-literature | 2025 Oct-Dec

REPOSITORIES: biostudies-literature