Optimizing the Straight Leg Raise Maneuver to Improve Prediction of Conclusive Gastro-Esophageal Reflux Disease.

ABSTRACT:

Background

Gastroesophageal reflux disease (GERD) arises from dysfunction of the anti-reflux barrier. While high-resolution manometry (HRM) is routinely performed in suspected GERD, traditional metrics are poor predictors. The routine adoption of the straight leg raise (SLR) maneuver has unveiled a series of unaddressed challenges. This study aimed to determine the minimum intra-abdominal pressure (IAP) increase for effectively stressing the esophago-gastric junction (EGJ), the optimal intra-esophageal pressure (IEP) increase threshold for GERD prediction, and explore EGJ behavior in GERD and non-GERD patients.

Methods

We performed a retrospective review of HRM tracings and pH-impedance studies of consecutive adult patients with GERD symptoms. Peak and mean IAP and IEP durin

SUBMITTER: Siboni S 

PROVIDER: S-EPMC12623283 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature