Modified geriatric nutritional risk index: a high-sensitivity marker with L-shaped association for sarcopenia in hospitalized older adults.

ABSTRACT:

Background

Screening for sarcopenia in older inpatients is currently inadequate, primarily because of the lack of consideration of the interaction between inflammation and nutrition. This study aimed to assess the efficacy of a novel modified Geriatric Nutritional Risk Index (mGNRI), which incorporates C-reactive protein (CRP) levels and weight changes, in predicting sarcopenia compared to traditional indices (geriatric nutritional risk index, GNRI/nutritional risk index, NRI).

Methods

In this cross-sectional study, we evaluated 153 hospitalized older patients (mean age, 80.2 ± 9.1 years) using comprehensive assessments. Sarcopenia was diagnosed based on the Asian Working Group for Sarcopenia (AWGS) criteria, which include muscle mass and strength/function. We analyzed the a

SUBMITTER: Wei H 

PROVIDER: S-EPMC12623325 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature