Antibiotic optimization in hospitalized children with non-severe community-acquired pneumonia: lessons from an antimicrobial stewardship intervention (2022-2024).

ABSTRACT:

Background and objectives

Community-acquired pneumonia (CAP) is a leading cause of hospitalization and antibiotic use in children. Despite guidelines recommending narrow-spectrum regimens and shorter treatment durations, prescribing practices remain inconsistent. This study assessed the impact of a newly implemented diagnostic and therapeutic clinical pathway (CP) as part of an antimicrobial stewardship (AMS) intervention in a tertiary care pediatric hospital.

Methods

A single-center, retrospective observational study was conducted on children aged 28 days to 18 years hospitalized with non-severe, uncomplicated CAP from January 2022 to December 2024. The CP was implemented on January 1st, 2024. Antibiotic prescribing patterns, clinical outcomes, and predictors of short-cours

SUBMITTER: Attaianese F 

PROVIDER: S-EPMC12623335 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature