Determinants of metabolic syndrome in people living with human immunodeficiency virus in Africa: a systematic review and meta-analysis.

ABSTRACT:

Background

Metabolic syndrome (MetS) among people living with HIV (PLHIV) is an emerging concern in Africa, but its underlying causes remain unclear. This study is a systematic review and meta-analysis of observational studies published between January 2000 and June 2025 to synthesize evidence on the determinants of MetS among PLHIV in Africa.

Methods

PubMed, Web of Science, Scopus, and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases were searched for studies reporting determinants of MetS among PLHIV in Africa. Two reviewers independently screened and extracted data, and the risk of bias was assessed with the Newcastle-Ottawa Scale.

Results

Thirty-six studies were included, while 23 were meta-analyzed. Female sex was strongly associated wi

SUBMITTER: David EA 

PROVIDER: S-EPMC12623360 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature