The effect of Chinese medicine therapeutics on HIV/AIDS: a systematic review and network meta-analysis.

ABSTRACT:

Background

Although antiretroviral therapy (ART) effectively suppresses HIV, incomplete immune reconstitution affects 20%-30% of adherent patients. Chinese Medicine (CM) demonstrates potential as a complementary therapy for human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS), yet its long-term impact on immune recovery remains unestablished. This network meta-analysis (NMA) aimed to compare CM interventions for enhancing CD4⁺ T-cell counts and overall efficacy in HIV/AIDS management.

Methods

We systematically searched PubMed, Embase, Web of Science, and the Cochrane Library from inception to 27 August 2024 for randomized controlled trials (RCTs) and observational studies on CM for HIV/AIDS. Bayesian NMA was conducted using R 4.2.2 with BU

SUBMITTER: Hongxi W 

PROVIDER: S-EPMC12623377 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature