Genotyping of Acinetobacter baumannii clinical isolates from Polish hospitals uncovers novel sequence types.

ABSTRACT: Acinetobacter baumannii is an opportunistic pathogen associated with healthcare-acquired infections. This study examined the clonal relatedness and drug resistance of 38 clinical isolates of A. baumannii from three hospitals in Poland and five isolates from pig manure. PFGE analysis identified seven clusters (A-G); of these, clusters A and B comprised the majority of clinical isolates, while A and C were dominated by the pig manure isolates, and cluster C included the reference strain ATCC 17978. MLST analysis of the clinical isolates revealed nine sequence types (STs), including three previously-unreported types with a newly-discovered gdhB gene allele. Three new STs were detected in the same hospital. Most isolates belonged to the international clonal complex 2 (IC2), a key contributor t

SUBMITTER: Sidor-Dzitkowska K 

PROVIDER: S-EPMC12623429 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature