Different Brain Network Connectomic Relationships Subserve Hand Dexterity During Task Versus Resting States in People with Brain Tumors.

ABSTRACT:

Purpose

The purpose of this study was to explore different brain network connectomic relationships subserving hand dexterity in patients with contrast-enhancing brain tumors during task and resting states.

Method

We measured hand dexterity, resting state functional connectivity, and task-based functional connectivity in 21 participants with newly diagnosed brain tumors. Hand dexterity was measured using the 9-hole peg test (9HPT), and patient-reported outcomes were assessed with the Duroz Hand Index (DHI).

Findings

We discovered the following: (1) The inability to complete dexterous tasks is most associated with low somatomotor-basal ganglia network connectivity during rest but high somatomotor-basal ganglia network connectivity during tasks; (2) in the subgroup of be

SUBMITTER: Boerger TF 

PROVIDER: S-EPMC12623447 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature