Leukemia Incidence and Demographic Trends in Saudi Arabia, 1997-2022: A Nationwide Registry Analysis.

ABSTRACT:

Background

Leukemia presents a significant and evolving public health challenge in Saudi Arabia, yet long-term nationwide epidemiological trends are unavailable. This study aimed to characterize temporal, demographic, and regional patterns in leukemia incidence from 1997 to 2022.

Methods

We conducted a retrospective nationwide analysis using the Saudi Cancer Registry and Global Burden of Disease data. We calculated age-standardized incidence rates (ASR), age-specific incidence rates (AIR) per 100 000, and average/annual percentage changes (AAPC/APC) by age, sex, leukemia type, and administrative region.

Results

The overall ASR was 5.9, with an increase over time (AAPC = 2.28, 95% CI 1.68‒2.87), sharply accelerating after 2016 (APC = 9.47, 95% CI 6.21‒15.18). This tren

SUBMITTER: Almasmoum HA 

PROVIDER: S-EPMC12623604 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature