Ophthalmic complications associated with COVID-19: a large US national database analysis.

ABSTRACT:

Objective

To assess ophthalmic complications following COVID-19 infection and the impact of mRNA vaccination.

Methods

A retrospective cohort analysis was conducted using a large US database of de-identified electronic health records (1 March 2020-30 April 2021). Patients with COVID-19 and subsequent ophthalmology evaluation were included. The vaccinated COVID-19 cohort was matched to an unvaccinated cohort (n = 73,654 each). COVID-19 and influenza patients (n = 77,809 each) were also matched. Influenza served as a historical control. Ten ophthalmic conditions were assessed post-COVID-19 infection, including retinal artery occlusion (RAO), retinal vein occlusion (RVO), retinal oedema, vitreous haemorrhage, and neuro-ophthalmic manifestations. Bonferroni correction addressed m

SUBMITTER: Azar AE 

PROVIDER: S-EPMC12623750 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature