Functionalized magnetic nanoparticles with deep eutectic solvents as efficient catalyst for the green synthesis of dihydroquinazolinones.

ABSTRACT: In this study, deep eutectic solvents were attached to SiO₂-coated magnetic nanoparticles through a linker. The resulting nanomagnet-immobilized arginine/choline chloride designated as MNP@Arg/ChCl was characterized using FT-IR, XRD, TGA, VSM, and SEM techniques. The catalyst showed an irregular spherical morphology, and the mean particle diameter was determined to be about 39.9 nm. TGA analysis also confirmed that the catalyst remained thermally stable up to approximately 225 °C. MNP@Arg/ChCl demonstrated excellent catalytic activity in the solvent-free synthesis of 2,3-disubstituted-2,3-dihydroquinazolin-4(1 H)-one derivatives via a three-component reaction involving isatoic anhydride, amines, and aldehydes. The scope of this method was assessed using various aromatic aldehyde

SUBMITTER: Valipour Z 

PROVIDER: S-EPMC12623933 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature