The resilience of vaccine serotypes in adult invasive pneumococcal disease in Portugal, 2018-2023.

ABSTRACT: In Portugal, after a decline in the proportion of adult invasive pneumococcal disease (IPD) associated with serotypes included in PCV7 and PCV13 attributed to their use in children, we observed a stabilization in the number of IPD episodes caused by serotypes included in conjugate vaccines, suggesting that no further benefit could be expected from pediatric vaccination. Worldwide, the COVID-19 pandemic and the measures adopted to contain viral transmission had major impacts on other respiratory transmissible pathogens, including pneumococcal infections. Many countries reported a decline in IPD cases, followed by an increase, coinciding with the relaxation of those measures. In Portugal, between 2018 and 2023, we found a pronounced decrease in the number of IPD samples in 2019-2021 (76% red

SUBMITTER: Guerreiro-Nunes A 

PROVIDER: S-EPMC12624040 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature