Systemic immune-inflammation index and pan-immune value as prognostic indicators of clinical outcomes in mycosis fungoides: A retrospective cohort study.

ABSTRACT: Blood inflammatory markers may provide prognostic insights but remain underexplored in mycosis fungoides (MF). To evaluate the prognostic significance of baseline blood inflammatory markers, including the neutrophil-to-lymphocyte ratio (NLR), eosinophil-to-lymphocyte ratio (ELR), monocyte-to-lymphocyte ratio (MLR), pan-inflammation value (PIV) and systemic immune-inflammation index (SII), in MF. This retrospective cohort study included MF patients diagnosed between 1997 and 2024 at a tertiary medical centre. Markers were analysed in relation to MF stage, morphology, overall survival (OS) and progression-free survival (PFS). Among 195 patients, all markers were significantly elevated in advanced-stage MF compared to early-stage MF. Marker levels generally increased from patch to tumour-stag

SUBMITTER: Jung JM 

PROVIDER: S-EPMC12624204 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature