Identification of embryonic yield-related serum biomarkers using proteomic analysis in ovine superovulation.

ABSTRACT: Superovulation is an efficient technology for the propagation of excellent livestock. Blood proteins other than reproductive hormones might be related to the outcome of superovulation. In this study, to identify potential protein biomarkers, the serum proteome of superovulation donor ewes was analyzed. The ewes were classified into spontaneous estrus (SE) and induced estrus (IE) groups, and their blood samples were collected before the first follicle-stimulating hormone (FSH) injection. Then, high (HEY) and low embryonic yield (LEY) populations of each group were identified based on the total embryonic number. Five donors from each population were selected for serum proteomic analysis. Finally, partially differentially expressed proteins (DEPs) were verified using the enzyme-linked immunos

SUBMITTER: Su X 

PROVIDER: S-EPMC12624267 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature