Sex Differences in Mortality and Receipt of Kidney Replacement Therapy Among Adults With Stage 5 Chronic Kidney Disease.

ABSTRACT:

Importance

Female individuals typically outlive male individuals in the general population. Whether this survival advantage persists among adults with stage 5 chronic kidney disease (CKD) is unknown.

Objective

To examine sex differences in mortality and treatment with kidney replacement therapy (KRT; including dialysis and transplant) among adults with incident stage 5 CKD.

Design, setting, and participants

This population-based cohort study used linked administrative and kidney care program data from Alberta, Canada. Adults 18 years and older with incident non-KRT-dependent stage 5 CKD were identified between April 2005 and March 2019 and observed from study entry until death, out-migration, or March 2021. Data were analyzed from January to August 2025.

Main outco

SUBMITTER: Chan C 

PROVIDER: S-EPMC12624453 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature