Scalp and auricular acupuncture attenuate recurrent gastroesophageal reflux disease and related inflammatory cytokines.

ABSTRACT:

Background

Gastroesophageal reflux disease (GERD) is increasingly common in developed countries. The pathogenesis involved in the symptoms includes gastric acid, esophageal or gastric motility disorders, visceral hypersensitivity, and lower esophageal sphincter (LES) dysfunction. Proton pump inhibitors (PPIs) are the most effective treatment, but long-term use can lead to gastric hypoacidity and nutrient deficiencies.

Aims

This study exams the potential of meridian acupoint stimulation to modulate visceral hypersensitivity and LES tone in patients who are dependent or have failed PPIs. Scalp acupuncture activates the trigemino-parasympathetic reflex, while auricular acupuncture stimulates the vagus nerve, affecting the autonomic nervous system (ANS) of the viscera. This appr

SUBMITTER: Wen TK 

PROVIDER: S-EPMC12624676 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature