Global prevalence of autoimmune diseases in turner syndrome: a systematic review and meta-analysis.

ABSTRACT:

Objective

Despite previous research linking Turner Syndrome (TS) with specific autoimmune conditions, a comprehensive analysis examining the broader relationship between sex chromosome abnormalities and multiple autoimmune diseases (AIDs) is lacking. This study aims to provide a meta-analysis of AID prevalence in TS, highlighting clinical implications and potential genetic links.

Methods

A systematic search of Medline, Embase, Scopus, and Web of Science was conducted from database inception to July 30, 2024, using search terms including "Turner Syndrome," "sex chromosome abnormalities," and "autoimmune diseases." Duplicate entries were removed, and three authors independently screened the titles and abstracts, resolving discrepancies through consensus. Eligible studies inclu

SUBMITTER: Hwang S 

PROVIDER: S-EPMC12624938 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature