Risk factors for severe disease in children hospitalized with SARS-CoV-2 infection in China: a retrospective cohort study.

ABSTRACT:

Background

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has spread rapidly worldwide since its emergence in 2019. While infections in children are generally mild, severe disease can occur in some rare cases. Herein, we aim to identify risk factors for severe disease in children hospitalized with SARS-CoV-2 infection during the post-Omicron period.

Methods

This retrospective cohort study was based on a review of the records of children aged under 15 years hospitalized with SARS-CoV-2 infection at a university hospital in Xi'an, China between December 8, 2022, and January 17, 2023. Multivariable logistic regression was applied to identify factors associated with severe disease.

Results

Of 164 children included in the analysis, 33 had severe dis

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12624980 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature