Effectiveness and safety of automated insulin delivery in type 2 diabetes: a meta-analysis.

ABSTRACT:

Background

The automated insulin delivery (AID) systems are increasingly used in patients with type 2 diabetes requiring insulin therapy. This study aims to evaluate the effectiveness and safety of AID systems in type 2 diabetes.

Methods

Embase, PubMed, Web of Science, the Cochrane Library, and ClinicalTrials.gov website were searched until 25 May 2025. Randomized controlled trials (RCTs), single-arm trials, and real-world evidence (RWE) studies comparing AID with conventional insulin therapy in type 2 diabetes were included. Time in range (TIR, 3.9-10 mmol/L) was the primary outcome. Secondary outcomes included time below range (TBR, < 3.9 mmol/L), time above range (TAR, > 10 mmol/L), HbA_1c level, and safety outcomes.

Results

This meta-analysis included 10

SUBMITTER: Zeng B 

PROVIDER: S-EPMC12624994 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature