Patrilineages of ethnolinguistically diverse populations reveal multifactorial influences on Chinese paternal population stratification.

ABSTRACT:

Background

Large-scale Y-chromosome genetic resources provide critical insights into human evolutionary history. However, the limited high-density Y-chromosomal data from ethnolinguistically diverse Chinese populations hinder the reconstruction of fine-scale population stratification and the exploration of its complex influencing factors.

Objectives

We report microarray-based high-density Y-SNP data from 5311 unrelated males in the pilot phase of the 10K Chinese People Genomic Diversity Project (10K_CPGDP) and merge it with spatiotemporally high-coverage reference data from both ancient and modern individuals from public sources and the Huaxi Biobank dataset.

Results

We identified clear north-south and west-east genetic substructures among Chinese populations, reflect

SUBMITTER: Yang T 

PROVIDER: S-EPMC12625027 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature