Musculoskeletal modelling sequentially integrated with stress simulation reveals asymmetrical knee loading and ligament stress during long-distance running.

ABSTRACT:

Background

Understanding the internal load characteristics of the knee joint is essential for investigating unilateral knee injuries associated with running. This study examined the differences in the location and magnitude of von Mises stress in the internal structures of bilateral knee joints during the stance phase of gait following 10 km running at submaximal speeds.

Methods

A healthy male recreational runner participated in this study. We employed a synergistic approach, integrating subject-specific knee joint angles, reaction forces, and moments derived from musculoskeletal modeling to inform and drive the finite element (FE) modeling of running. This methodology ensured a detailed and accurate representation of knee joint mechanics. The peak stresses of the bilateral

SUBMITTER: Gao Z 

PROVIDER: S-EPMC12625068 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature